During the Proton Driver design study based on an 8 GeV superconducting RF H- linac, a major concern is the feasibility of transport and injection of high energy H- ions because the energy of H- beam would be an order of magnitude higher than the existing ones. This paper will focus on two key technical issues: (1) stripping losses during transport (including stripping by blackbody radiation, magnetic field and residual gases); (2) stripping efficiency of carbon foil during injection.